Outthinking and
Outpacing Cancer

A New Decision Intelligence and Care Model to Battle Cancer

Our mission is not to keep up with cancer, but to outthink it and outpace it. The biggest barrier in cancer care is uneven access: to high-quality data, to oncologists, and often to care itself. Every patient facing cancer deserves treatment decisions that adapt as their tumor evolves, reflect their unique biology, anticipate resistance, and minimize toxicity - all with the shared goal of improving survival.

A New Operating System for Oncology

Driven by Agentic Biology and Chemical Intelligence

We are building a new operating system for oncology - one that captures every biological signal,
unifies all data streams, and utilizes computational intelligence.

We call this integrated biological intelligence:

A continuous learning model that integrates DNA, RNA, radiology, pathology, EHR data, labs, ctDNA, toxicity and
treatment history to compute the optimal therapy at every step.

As cancer evolves, our system evolves with it, helping oncologists deliver the best-matched treatment plan,
regardless of location or resource constraints.

New Data
Act
Re-Analysis
Recommend
Refine
Toxicity Alerts
resistance maps
outcome modeling
drug response predictions
Toxicity Alerts
Resistance Maps
Outcome Modeling
Drug Response Predictions
New Data
Act
Re-Analysis
Refine
Recommend

Cancer Intelligence

Our clinical reasoning agents evaluate treatment options, weigh risks and benefits, align with NCCN/ASCO/ESMO guidelines, explain therapeutic rationale and automatically re-run analyses whenever new data arrives.

This produces drug response predictions, resistance maps, toxicity alerts, and outcome modeling – not as static reports but as intelligent, operational tools.

Because intelligence only matters at the
point of care when it drives outcomes.

Introducing gSage Open

gSage Open is our cancer intelligence and care platform – an integrated system built to provide precision oncology workflow in the clinic.
It is the first platform designed to provide precision treatment matching at the point of care.

gSage Open can:

  • Predict response across 740+ FDA approved therapies
  • Map intrinsic and acquired resistance pathways
  • Work across any next generation sequencing report
  • Prioritize therapies based on benefit, resistance, and toxicity
  • Reduce trial and error decisions in treatment sequencing

Built to Learn, Simulate, and Stay Ahead of Cancer

gSage Open learns, updates, and evolves its recommendations, just like the oncologists it supports.It builds a digital twin of each cancer patient to simulate drug efficacy. It inspires the care team to stay in continual learning mode to outthink and outpace cancer.

We invite you to be among the first to
join the beta program for gSage Open

Powering Precision Drug Efficacy at Point of Care

Our GPT-driven platform is embedded in clinical workflow and treatment protocols.
We enable real-time decisions around first-line therapy, alternatives for emerging resistance,
optimal switch points, next-line strategies after progression, and trial matching based on ongoing biology.

gSage Open:

1

Reduces Failed Therapies

2

Anticipates Resistance Earlier

3

Minimizes Toxicities

4

Improves Treatment Sequencing

5

Supports Clinicians Navigating Complexity

Precision Oncology maximizes survival opportunities
for every patient – anywhere in the world.

gSage Patient App

Our app empowers patients with:

  • Personalized guidance
  • Wellness support
  • Smart health monitoring
  • Cognitive therapies
  • Real-time treatment insights tailored to their biology

Pioneering Health AI

In a world where healthcare is rapidly evolving, Pioneering Health AI is at the forefront of innovation. GeneSilico™ cutting-edge solutions are designed to empower medical professionals, optimize patient care, and transform the way health data is utilized.

From predictive diagnostics to personalized treatment plans, we harness the power of artificial intelligence to make healthcare smarter, faster, and more efficient.

Join Us in the Fight
Against Cancer

Together, we can reach more patients, improve survival, and transform outcomes. United
as one global team - with technology as our partner - we can advance, learn, and make a
meaningful difference for every person facing cancer.